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At least one-half of all anti-cancer drugs on the market come from natural sources (Sharifi-Rad et al., 2019)

Furthermore, homocysteine can be converted back into methionine through the utilization of betaine, a metabolite of choline, which acts as a methyl donor in a reaction catalyzed by betaine homocysteine methyltransferase (BHMT)

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In the United States, it is available for purchase online, but regulatory authorities do not sanction its use in humans

Chemosphere Mass-balance-model-based evaluation of sewage treatment plant contribution to residual pharmaceuticals in environmental waters