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Another study that evaluated the nutritional factors associated with late-onset dementia of the Alzheimers type concluded that the decreased levels of several vitamins including vitamin C may contribute to the development of AD ( Moreover, the biomarkers of oxidative damage to DNA such as 8-hydroxy-2-deoxyguanosine on lymphocytes are also increased in AD along with a decline in plasma antioxidants and vitamin C, A, and E as well as carotenoids such as lutein, -carotene, -carotene, and lycopene (Rinaldi et al., 2003)

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