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was attributed to the use of a centrifugation step during experimental procedures, as omitting this step resulted in decreased initial intracellular counts in both RAW264.7 murine macrophages and A549 human epithelial cells [Citation87], indicating that the flagellum is necessary for cell invasion and initiation of the intracellular lifecycle

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A 20-week facial exercise program, consisting of 30 min daily or every other day, brings modest improvements in the appearance of ageing faces, which is likely attributable to exercise-induced the hypertrophy of facial muscles [127]

They appear to be more likely in younger patients, but it's otherwise impossible to predict who will experience them