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The multiple myeloma cell line RPMI8226 (RRID: CVCL_0014) was acquired from ATCC and cultured as recommended (www.atcc.org/products/ccl-155)

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Anti-inflammatory effect of external use of escin on cutaneous inflammation: Possible involvement of glucocorticoids receptor

This does not affect the quality of the product Do not blend, add to a food processor or add to hot water Consult a healthcare practitioner before using this product if you are pregnant or breastfeeding, have a medical condition, or are taking any medication Contains alcohol If you would prefer not to consume any alcohol, most of it can be evaporated prior to consumption by opening the sachet and leaving the gel in the open air at room temperature for 30 minutes (maximum of 45 to 60 minutes) to ensure all the ethanol is evaporated

methodology, P.S., A.S., and M.F.H