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Cellular inputs that affect the relative concentrations of these couples oxidized and reduced species will shift their redox potential and tilt the thioldisulfide balance of their respective protein targets

Such modifications can occur as cotranslational or posttranslational events following incorporation of the amino acid into proteins (see Chapter 13)

Research has also linked choline deficiencies to nonalcoholic fatty liver disease [8]

Therefore, we believe that further studies are needed to define the therapeutic effect of these products and to determine the appropriate amounts of natural extracts, for the correct design of clinical trials