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1- O -hexyl-2,3,5-trimethylhydroquinone (BTT-105), an Nrf2 activator, alleviates MASH fibrosis by enhancing antioxidant pathways and suppressing phosphatidylinositol 3-kinase/protein kinase B (PI3K/AKT) signaling in hepatic stellate cells [37]

This oxidoreductase reaction necessitates the activity of the membrane-bound ER oxidoreductin 1 (Ero-1), a FAD-dependent oxidoreductase

S2024-JC-QN-0871 to H.Y.W)

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However, its application still faces challenges such as stability, matrix compatibility, sensory characteristics and standardization