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This depletion reduces the cells ability to neutralize ROS, leading to an imbalance in the redox state and promoting the accumulation of lipid ROS

Additionally, apigenin inhibits metastasis by down-regulating proteins involved in EMT and tumor cell invasion, such as Snail1, MMP-2, and MMP-9

IGF-1 levels and total SHIM score correlate significantly ( r =0.31, P =0.02), as do IGF-1 levels and all individual SHIM question scores, and IGF-1 levels and the sexual domain of the EPIC questionnaire ( r =0.30, P =0.02)

Reverse transcription-polymerase chain reaction (RT-PCR) TRIzol reagent was used to extract total RNA

[Google Scholar] Rani, P