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The miRNAs and long non-coding RNAs (lncRNAs) and extracellular vesicles (EVs) induced by viral factors MiRNAs and lncRNAs are two pivotal classes of regulatory RNAs

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120,121 In atherosclerosis, a metabolic disease driven by chronic inflammation and faulty lipid metabolism, E3 ligases such as FBXW2 and FBXO3 have been identified as key modulators of vascular inflammation

The organism is ubiquitous with childhood acquisition seemingly being the role and may last for years or decades however, it is difficult to ascertain when infection occurs clinically hence seroprevalence data are the source of information of rates both in geographically and demographically diverse populations [2, 52, 58, 59, 60]