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Spindel ON, Yan C, Berk BC

Parkin (i.e., Park2) is an E3 ubiquitin ligase that is believed to play an important role in directing misfolded proteins for degradation via the ubiquitin-protease system 74 and helps regulate mitochondrial dynamics through mitochondrial biogenesis, import of mitochondrial proteins and mitophagy (targeting mitochondria to phagosomes) 75

PMID: 35 YeWXieTSongYZhouL

Antidiarrheals, such as Diphenoxylate hydrochloride (Lomotil), Metronidazole (Flagyl), Methylprednisolone (Medrol), and, Sulfasalazine (Azulfidine)

BLV exposure (area under the plasma concentration-time curve [AUC]) between ADA+ and ADA patients was similar for 2 mg, AUC ratio (90% CI)=1.22 (1.00-1.51) and for 10 mg, 1.12 (0.96-1.32)