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4 Although it is an off-label use, a single prophylactic treatment 1 to 4 times / month of 3 to 4 mg / kg of IV heme can prevent recurrent attacks

They used intermittent dosing, which was effective in approximately 80% of clomiphene-resistant patients (241)

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As the scientific community delves further into this area, additional transporters regulating other critical metabolites may be uncovered, broadening the landscape of potential therapeutic targets