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[55] Interestingly, hypothyroidism is highly prevalent in CKD, and a growing body of evidence suggests that hypothyroidism may be a risk factor for developing CKD, and worse health outcomes for those with CKD

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Leukemia 36 , 10881101 (2022)

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But a small 2018 study found that taking higher dosage oral supplements (1,000 to 2,000 mcg) improves B12 levels about as effectively as injections

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Vitamin B12 in Present Knowledge in Nutrition

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The GI system has already partially adapted to delayed gastric emptying

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