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The concept of bioavailability may, in part, also explain why the same dose may cause toxicity by one route (IV) but not the other (smoking)

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climate-related experiments and their implications Large temporal and spatial differences in environmental conditions are likely to accelerate as global warming continues (Collins et al., 2013)

Obese mice and rats treated with AOD9604 showed significant decreases in adipose tissue depot weights, reductions in adipocyte size observed histologically, and improvements in body composition measured by DEXA scanning or MRI