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264 Importantly, the harmonious cooperation of ZNRF3 and RNF43 restricts Wnt/-catenin activity and maintains homeostasis between proliferation and tumor formation

In contrast, acetaminophen may be an acceptable alternative therapy for pain management ( Adjuvant Analgesic Medications Lidocaine infusion is commonly known for its anti-inflammatory properties and opioid-sparing effect (Sun et al., 2012)

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Ca 2+ subsequently enters the mitochondrial matrix through the mitochondrial calcium uniporter to cause mitochondrial swelling and membrane potential collapse, ultimately leading to cell death (Fig