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The commenter also suggested that CMS establish a clear and consistent process for manufacturers to notify the agency of ASP restatements that occur after initial rebate invoices are issued, and for those ASP restatements to be fully accounted for in the Part B inflation rebate reconciliation

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Once opened, refrigerate at 28 C and use within 28 days

Given that neurological damage may be irreversible if treatment is delayed, proactive strategies are essential in UK clinical practice