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Note that selenium is also important to protect the thyroid from oxidative damage especially when using iodine as a supplement

(1) Direct antioxidant activity of NAC as an oxygen radical scavenger For a compound to act as an antioxidant in a biological matrix, its reaction rate with oxidants must be higher than that of endogenous antioxidants and much higher than that of the substrates present [37]

Roderique JD, Josef CS, Newcomb AH, Reynolds PS, Somera LG, Spiess BD

Esculin can inhibit oxidative stress in liver injury, as esculin (10-40 mg/kg) can activate the Nrf2 signaling pathway to increase HO-1 expression levels and decrease the MDA content in lipopolysaccharide (LPS)/D-galactosamine-induced acute liver injury mice (61)

Mass Spectrom Rev 37(6):772792 lvarez R (2020) Non-targeted metabolomic analysis reveals serum phospholipid alterations in patients with early stages of Diabetic Foot Ulcer