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10.1016/j.watres.2018.10.068 [PubMed: 30408731] [CrossRef] Tovar AP, Navalta JW, Kruskall LJ, Young JC (2017)

This reversible regulation is not just a protective measure

In models of Alzheimer's disease (AD), CR offers multiple benefits: it increases the production of antioxidants and anti-apoptotic proteins, boosts histone deacetylase activity, and elevates levels of brain-derived neurotrophic factor (BDNF)