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B 8 , 65176529 (2020)

( F ) Luminescence recorded from HeLa cells either expressing or not expressing APEX2, pre-treated for 20 min with luminol and substrate (HPI) (250 M each), and then exposed to H 2 O 2 (50 M)

Additionally, wrinkle volume reductions of up to 55.8% have been measured in 12-week topical studies

Alternative options include propylthiouracil, although cross-reactivity with methimazole has been reported, as well as definitive interventions such as radioactive iodine ablation or thyroidectomy