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This peptide can get into the nucleus and compete with endogenous ATF5 for partner proteins or DNA-binding sites, thereby blocking its transcriptional activity

Fogacci et al

The large variabilities in safety outcomes reported in the studies, coupled with several unreported outcomes, may indicate that we have little knowledge about the effect of the service on safety outcomes, prompting the need for further investigation

Morphological changes in the cornea and lens were monitored via slit lamp microscopy at various time points after exposure

221,222 Deleted in breast cancer 1 (DBC1) and active regulator of SIRT1 (AROS) are two proteins that are able to bind to SIRT1, whereas their interactions present opposite functions