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After that, the supernatants stored at 80 C and used for antioxidant and biochemical assays

In relation to the EULAR recommendation, where no consensus was reached on the possibility of using CNS-acting medications in the treatment of comorbidities such as sleep disorders, neurologists agreed on the choice between antidepressants or anticonvulsants on medical judgment when there is a comorbidity for depression or anxiety

Adhere to Ethical and Regulatory Standards: Ensure all research is conducted ethically and complies with relevant institutional and national regulations

Involvement of the microbiota-gut-brain axis in chronic restraint stress: disturbances of the kynurenine metabolic pathway in both the gut and brain

1st infusion = 150 mg/kg over 60 minutes