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doi: 10.1007/s00428-014-1588-4 139 ZhangBBieQWuPZhangJYouBShiHet al

Cells can stave off ferroptotic fate through the use of antioxidant pathways that largely utilize GSH, glutathione peroxidase 4 (GPX4), and perioredoxin-thioredoxin, which all ultimately rely on NADPH for regeneration

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

For example, for specific imbalances in the gut microbiota, corresponding probiotics should be selected for supplementation to restore the balance of the microbiota