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discovered that in mouse MCs, knocking down ROCK restored impaired fatty acid metabolism by modulating metabolic regulators like AMPK, PGC-1, and CPT-1 [78]

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Specifically, Prevotella copri produces succinic acid, which binds to succinate receptors on dendritic cells, enhancing antigen-specific T cell responses and contributing to host immune defense mechanisms (Dan et al., 2020)