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Clinical literature suggests that the body retains methylcobalamin in the tissues slightly longer than synthetic forms, making it the preferred choice for individuals specifically looking to address neurological symptoms, brain fog, and nerve damage

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Elevated levels of calcium in the blood are referred to as hypercalcemia

McElheron of Trinity College Dublin for assistance with the Luminex assays

Accordingly, the present review acknowledges the conceptual importance of this literature while restricting systematic synthesis to naturally occurring alkaloids to preserve translational relevance to kratom use and dependence