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Studies have found that high oxidative stress levels (e.g., increased intracellular superoxide anion, oxidized glutathione, XO activity, etc.) and oxidative damage (e.g., elevated malondialdehyde, 8-oxodeoxyguanosine levels) in leukocytes from aged mice and peripheral blood immune cells from elderly humans are consistent with impaired immune responses

Pre-treatment of MM cells with docosahexaenoic acid (DHA) or eicosapentaenoic acid (EHA) also increased the sensitivity to bortezomib by altering the GSH metabolic pathway (98)

doi:10.20945/2359-3997000000066

Front Plant Sci 9:605

In this context, the use of probiotics has been studied as it appears that they may reduce the rate of pulmonary exacerbations in the disease (117, 118)