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Safety and translational challenges are considerable and must drive clinical application: immune stimulation carries theoretical risk as well as known risk of worsening autoimmune phenomena or inflammatory toxicities, particularly in the setting of active immunosuppression (e.g., newly diagnosed with cytotoxic therapy, on high-dose steroids)

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Make the call with your clinician, who will set the route, dose, timing, and monitoring based on your goals and health history