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[DOI] [PubMed] [Google Scholar] 112.Kwan S.T.C., King J.H., Yan J., Jiang X., Wei E., Fomin V.G., Roberson M.S., Caudill M.A

Enzymatic Antioxidants Enzymatic antioxidants function by converting oxidized metabolic products in a multi-step process to hydrogen peroxide and then to water using cofactors such as iron, zinc, copper, and manganese

Mao found that treating cancer cells with GPX4 inhibitors resulted in acute depletion of N-carbamyl-L-aspartate (C-ASP, a pyrimidine biosynthesis intermediate), accompanied by accumulation of uridine, which could be inhibited by fer-1, a ferroptosis inhibitor [18]

2012 Dec;6(6):683-704

For this reason, folic acid supplements may mask vitamin-B12-induced megaloblastic anemia and cause an underlying vitamin B12 deficiency to go undetected ( Megaloblastic anemia is a condition characterized by enlarged red blood cells