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and increased hydrolysis of MTXPGs by lysosomal gamma-glutamyl hydrolases (GGH) (2325), although the influence of GGH on MTX efficacy remains controversial (2628)

These techniques may facilitate a deeper understanding of the pathological effects of OH and improve its utility in clinical diagnostics [123]

Secretagogin regulates insulin signaling by direct insulin binding

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As a result, the majority of cases were not linked to known genetic illnesses, suggesting that secondary mitochondrial dysfunction may play a role [14] (Table 1 )