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Regulation of cholesterologenesis by the oxysterol receptor, LXRalpha

discussion 471, 2002

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When AGE-RAGE binding occurs, a signaling cascade activates proteins and kinases which eventually converge on IB, whose phosphorylation results in degradations allowing translocation of NF-B from the cytoplasm to the nucleus promoting transcription of pro-inflammatory genes (7375)

Of all the peptides marketed to women, exactly one holds an FDA-approved indication for a women's health condition: PT-141 (bremelanotide) , approved in 2019 for hypoactive sexual desire disorder in premenopausal women