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Nat Med 17(3):377382 Costa V, Scorrano L (2012) Shaping the role of mitochondria in the pathogenesis of Huntingtons disease

The release of IL-6, TNF-, and other proinflammatory cytokines triggers activation of key intracellular signaling cascades, including nuclear factor-kappa B (NF-B) and mitogen-activated protein kinase (MAPK) pathways (39, 40)