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Front Neurol 8:182 Xu D, Shan B, Sun H, Xiao J, Zhu K, Xie X, Li X, Liang W, Lu X, Qian L (2016) USP14 regulates autophagy by suppressing K63 ubiquitination of Beclin 1

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TMT reporter ion intensities were normalized to the median summed signal intensity across channels, and the data were filtered to retain proteins with at least two distinct peptides

Autophagy maintains cellular homeostasis and energy production, to allow cells to function normally, and is a protective mechanism induced in response to multiple stressors [7, 8]