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The serial ctDNA analyses detected an emergence of mismatch repair gene MSH2 and MSH6 gene mutations, which is associated with hypermutation and potential development of TMZ resistance during treatment with TMZ

[DOI] [PubMed] [Google Scholar] 4.Ferrari R, Bachetti T, Confortini R, Opasich C, Febo O, et al

Then, the cells were exposed to increasing concentrations of NADPH

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