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Diabetic polyneuropathy (DPN) is the most common late complication of diabetes mellitus

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iii- toxin based suicide gene therapy: a DNA construct, encoding for a toxic polypeptide whose expression is regulated by a specific transcription regulation element, is delivered to a heterogeneous cell population [179]

This work was supported by National Institutes of Health Intramural Research Program funding ZIA-DA000635 (NIDA/NIAAA Clinical Psychoneuroendocrinology and Neuropsychopharmacology Section