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OS typically arises from a disruption of the oxidant/antioxidant balance and can drive both neuroinflammatory and neurodegenerative processes, including those observed in MS (Kracun et al., 2025) (Figure 1)

Autism Res Treat 2014:472120, 2014 [DOI] [PMC free article] [PubMed] [Google Scholar] 63.Tager-Flusberg H, Rogers S, Cooper J, et al

10.1016/S0306-4522(99)00580-1 95 LaureysG.ValentinoM.DemolF.ZammitC.MuscatR.CambronM.et al

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In human cells, it has been shown that Prx5 can be targeted to mitochondria, peroxisomes, cytosol, and nucleus