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If your vitamin B12 is part of a multivitamin containing iron or calcium, these minerals are well-known causes of constipation

People taking newer selective 5-HT3 receptor antagonists, such as ondansetron or granisetron, for nausea treatment are less likely to have restless legs syndrome diagnosed because these drugs do not bind to dopamine receptors

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In many cases, temporary pain results from a clear event, like intense exercise, prolonged standing, or an awkward sleeping position

Niafar, Mitra, et al