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Another barrier is that some of the viral genome is inserted into host chromosomes, which can generate viral proteins

Figure 1 Other essential genes associated with ALD Certain loci confer a higher risk of ALD ( methylenetetrahydrofolate reductase (MTHFR), interleukin 1 (IL1B) , NFE2L2, RASGRF2 , CYP2E1, DRD2, TM6SF2, MBOAT7 , and PNPLA3 that were reportedly associated with the phenotype

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599 Additionally, Ndfip1 prevents increased expression of ACSL4, significantly improves motor dysfunction, and antagonizes the loss of dopaminergic neurons by inhibiting ferroptosis, 599 indicating that Ndfip1 may be a promising target for iron-related diseases, including PD

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