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For perimenopause specifically, hormonal fluctuation drives many of the most disruptive symptoms estrogen can spike and crash erratically, which is why some patients feel worse in early perimenopause than in full menopause

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Cerebrolysin peptides as mood stabilizers Zh Nevrol Psikhiatr Im SS Korsakova 2019;119(8):75-83

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The design of the trial was based on the premise that there is a common pathological mechanism in different types of pulmonary fibrosis that can be targeted irrespective of the underlying cause of the fibrosing lung disease