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Herxheimer reactions however continued the days on IV ceftriaxone, despite trying to pulse the IV medication 4 days in a row per week, so she was subsequently taken off this protocol, and switched to IV doxycycline 200 milligrams per day, infused over a 2 hour time period along with Plaquenil, nystatin, and rifampin 300 milligrams PO BID

Disruption of MAM integrity can lead to increased ROS production, mitochondrial damage, and activation of inflammatory pathways (213)

One RCT with 19 schizophrenia patients reported that controlled-release melatonin 2 mg significantly improved sleep efficiency compared to placebo [47]

The significant increase in platelet levels from day 1 to 7 in the Cohort 2 LCLT group suggests that LCLT may have an antithrombotic effect, which could be beneficial for COVID-19 patients with a high rate of thrombosis-induced complications

Creatine: A substance found naturally in muscle cells