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The 2 individual patient-reported components (stool frequency and rectal bleeding) are part of the Mayo score and were not powered for statistical significance Correlation of depicted PROs to Week 6 and Week 52 primary end points was not evaluated in the analysis GEMINI I TRIAL EXPLORATORY END POINTS: PATIENT-REPORTED OUTCOMES Overall population compared with placebo Not powered for statistical significance

Research indicates it can help heal damage caused by factors like alcohol and nonsteroidal anti-inflammatory drugs (NSAIDs) and may improve conditions associated with "leaky gut" syndrome by stabilizing intestinal permeability

Purification of the crude by HPLC (eluent A 0.1% TFA in water, eluent B 0.1% TFA in acetonitrile/water 4/1 v/v, 50 C, detection at 215 nm, 3 mL min 1 , 010% eluent B in 5 min, then 1025% eluent B in 30 min, C18 column) furnished peptide 6 as a white solid after lyophilization (6.81 mg, 64%)

Heliyon 10 (15), e34916

Blood samples were collected from abdominal aorta and placed at room temperature for 2 h