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(5) current research must focus on the development of drugs that penetrate the BBB, facilitate cognitive processing, and protect against the loss of synapses and neurons

In fact, OATP1B1 has been observed in mice and human material to play a role in cholesterol homeostasis [42], which therefore may provide an additional explanation for the present results pending specific experiments that include a fluconazole condition in the investigation of the involvement of the transporter in human cholesterol disposition