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Many of the experiments reviewed here rely on pharmacologic G6PD inhibition or G6PD siRNA knockdown

Nikolich-Zugich J, Knox KS, Rios CT, Natt B, Bhattacharya D, Fain MJ (2020) SARS-CoV-2 and COVID-19 in older adults: what we may expect regarding pathogenesis, immune responses, and outcomes

ROS directly oxidize the glutaminase protein, altering its structure and function, and modulating metabolic pathways, including elevated mitochondrial ROS production, which further affects glutaminase activity