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Trends Cancer

Upon oxidation, it forms a disulfide-bonded dimer (GSSG)

Interactions between these loci and surrounding regulatory elements can influence disease phenotype and severity

(2016) Nrf2 is the key to chemotherapy resistance in MCF7 breast cancer cells under hypoxia, Oncotarget , 7 , 14659-14672, doi: Njlsson, R., and Norgren, S