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The highest concentration of glycerol that could be created in the spaces between ice crystals by freeze-concentration was found to be 73% w/w according to Rasmussen and Luyet [[47]], or 68% v/v, which is equivalent to 9.3M

Nassar D, Blanpain C

In contrast, LCACs are thought to have the potential to activate inflammation, activating the NF-B luciferase reporter gene in RAW 264.7 cells in an acyl chain length- and concentration-dependent manner, as well as the phosphorylation of JNK and ERK [54, 55]

They also alter the tumour microenvironment by suppressing NF-B-driven inflammation, reducing its support for cancer cell survival and metastasis

van der Pligt P, Wadley GD, Lee IL, Ebrahimi S, Spiteri S, Dennis K et al (2025) Antioxidant supplementation for management of gestational diabetes mellitus in pregnancy: a systematic review and meta-analysis of randomised controlled trials