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Stresses such as drought, salinity, extreme temperatures, and heavy metal toxicity compromise photosynthetic efficiency through stomatal limitations (reduced CO assimilation) and non-stomatal limitations (structural and biochemical damage) (Sharma et al

Similarly, in bipolar disorder, particularly during depressive episodes, patients exhibit altered energy metabolism marked by increased lactate levels and decreased glucose and glycine levels, which parallels results in ME/CFS that suggest TCA impairment and energy metabolism dysregulation (Yamano et al., 2016

Linking childhood trauma and dissociation to psychotic symptoms in major depressive disorder, bipolar disorders, and schizophrenia: A transdiagnostic examination using patient and clinician ratings

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