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doi: 10.36141/svdld.v36i2.7163 156 SchultzHHAndersenCBSteinbruuchelDPerchMCarlsenJIversenM

Conservative Approach: Pregnancy: Doctor consultation absolutely necessary Breastfeeding: Limited research available Trying to conceive: Better to avoid until conception Conflicting Views: experts generally safe recommend complete avoidance FDA has no official guidelines 2

mu-Opioid receptor down-regulation and cAMP-dependent protein kinase phosphorylation in a mouse model of chronic morphine tolerance

References: (1) Huang T, Zhang K, Sun L, Xue X, et al

it is not standard in UK clinical practice, where single-use Water for Injections BP is preferred