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whether contrast-induced oxidative stress acts as a direct trigger, or if other intermediates (e.g., endoplasmic reticulum stress and mitochondrial dysfunction) are involved, requires definitive validation

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LD formation in steatotic Zucker hepatocytes was also investigated

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2008, doi: 10.1016/j.abb.2008.01.028

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This finding is consistent with a study that found low-dose lithium to stabilize patients with Alzheimer's disease

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That is why its effect in studies extends far beyond the gastrointestinal tract, where it was originally discovered

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