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10.1016/j.redox.2020.101576 Redox Biol

In summary, these therapeutic implications of drugs on RA ( Table 2 ), are designed to optimize the hypoxic microenvironment through multifaceted pathways, ultimately curbing inflammation and mitigating tissue damage, thereby achieving the desired therapeutic outcomes for autoimmune diseases

Structureactivity relationship (SAR) analyses via analog-by-catalog Among these inhibitory candidates, we focused on compounds C7 and C6 for their similar molecular structures (Fig