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Generally, the 1 H-MRS studies show inconsistent findings due to different metabolites, age of the participants, the methodological techniques, and the brain region of interest

Third-party testing is the minimum standard

Specifically, KLF expression by ECs markedly declines with age, contributing to reduced eNOS levels [214, 215]

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J Proteom 170:117129 Charlier JB, Polese C, Nouet C, Carnol M, Bosman B, Kramer U, Motte P, Hanikenne M (2015) Zinc triggers a complex transcriptional and post-transcriptional regulation of the metal homeostasis gene FRD3 in Arabidopsis relatives