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Iron is released into the cytoplasm by DMT1 overexpressed in the ectopic endometrium, induces oxidative stress via the Fenton reaction, leading to lipid peroxidation and ferroptosis (59)

Part of the reason for the early disregard for necrotic cell death was probably due to the fact that in contrast to apoptosis, necrosis was considered to be an unregulated form of cell death, which occurred once cellular integrity was compromised due to a multitude of insults

Reduced NEAT, lowered basal metabolic rate, persistent fatigue