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Still, as HLRCC tumours are rare and there is a lack of genetic information, it is unknown whether these oncogenic events occur due to additional genetic mutations, or if they are a direct consequence of FH loss

Although these are associated with many untoward side effects and often cannot be used for more than 6 months or two years

Emodin regulates the autophagy via the miR-371a-5p/PTEN axis to inhibit hepatic malignancy

doi: 10.3389/fnmol.2025.1623321 Received 05 May 2025 Accepted 10 June 2025 Published 25 June 2025 Volume 18 - 2025 Edited by Jonasz Jeremiasz Weber, Ruhr University Bochum, Germany Reviewed by Adriana Jimnez, Hospital Jurez de Mxico, Mexico Ana Aragn-Gonzlez, University of Oxford, United Kingdom Updates Copyright 2025 Wang, Chen, Chen, Mu and Chen

HRMS [M + H] (C 23 H 21 N 2 O 2 ): Calculated: 357.1603