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A recent study reported that spleen stiffness measurement is less influenced by liver inflammation and can facilitate fibrosis assessment in untreated AIH patients [161] The hepatic cut-off with the highest sensitivity and specificity for advanced fibrosis in AIH is 10.5 kPa

Nature Reviews Molecular Cell Biology (2021) 10

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Furthermore, we performed in situ proximity ligation assays (PLA) in this cell line and found that RSMC displayed strong signals with either Sororin or the structural subunit SMC3 (Fig

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