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HuangS-FOthmanAKoshkinAFischerSFischerDZamboniNet al

Western blotting analysis Tissues or cells were resuspended in lysis buffer on ice for 5 minutes, and the supernatants were collected after centrifugation at 13,000 g for 15 minutes

Dose-response curves for each compound were done in at least four independent experiments each in triplicate

Nat Rev Endocrinol (2020) 16:8190

Mutations in genes such as SNCA, LRRK2, PARK7, PINK1, and VPS35 are associated with familial forms of PD, while pesticide exposure, heavy metals, and industrial chemicals contribute to sporadic cases